The " CirB-RNA " cohort aims to create a biological collection associated with clinical and biological data from patients with hepatitis B infection. This project is part of a much larger program that aims to characterize and quantify circulating viral RNAs as a possible new biomarker of hepatitis B functional cure.
Adults patients and minor children over 6 years of age (in Lyon) with acute or chronic hepatitis B or presenting with HBsAg loss (with/without HBs seroconversion). (Co-infected patients with HDV and/or HCV and/or HIV are eligible)
Patients requiring blood sampling for medical care at the time of the medical appointment.
Informed patients who do not refuse to participate.
Persons not affiliated to a social security scheme and persons receiving medical assistance from the state may be asked to participate in the study
Patients participating at the time of the inclusion to an interventional trial evaluating a drug likely to interfere with this study.
Persons deprived of their liberty by a judicial or administrative decision
Adults who are subject to a legal protection measure
Children less than 6 years old (in Lyon)
Patients with hepatitis B infection (acute or chronic) or presenting with HBsAg loss (with/without anti-HBs seroconversion).
Cohort
Prospective
Blood sampling
Other interventionBlood sampling at each clinical follow-up visit.
Number of plot samples collected
The aim of this study is the constitution of a cohort with biological collection associated with clinical and biological data Data and samples will be collected at each follow-up visit until end of project (longitudinal study). This cohort is the first step of a research program and will be use in further study which are part of this research program. All studies of this research program aim to improve knowledge about hepatitis B, develop and validate a new biomarker of hepatitis B cure.
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