Criteria for Selecting First-line Metastatic Treatment for Patients With Urothelial Carcinoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France

About this trial

The standard first-line treatment for metastatic urothelial carcinoma has become the combination of Enfortumab Vedotin and Pembrolizumab following the publication of the EV-302 study results at the end of 2024. Another standard remains in 2025 for patients who are not eligible for the EV Pembrolizumab combination, namely platinum-based chemotherapy +/- avelumab in cases of non-progression. The objective of the FLORAL study is to determine the characteristics of these patients and the reasons that led clinicians to prefer a first-line treatment based on platinum salts.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients over 18 years of age

Metastatic urothelial carcinoma

Treated with first-line metastatic therapy since October 2024

Disqualifiers

Patient who expressed opposition to participating in the study

Trial population

Adut atient with metastatic urothelial carcinoma and reated with first-line metastatic therapy since October 2024

Trial design

Design model

Case-only

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Description of the clinical characteristics of patients recently treated with first-line metastatic therapy for urothelial carcinoma

Time frame
Up to 12 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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