Cryopreservation of Ovarian Tissue
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeUp to 45
SponsorWeill Medical College of Cornell University
About this trial
The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Females 0-45 years of age who are premenopausal
Treatment plan that will likely result in premature menopause or premature ovarian failure
Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy
Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients
Disqualifiers
Patients not meeting the above criteria
Patients who have not received medical clearance from their physicians to undergo surgery
Patients already experiencing menopause.
Trial design
Design model
Single group
Treatments tested in this trial
surgery to remove ovaries or high dose chemotherapy
Procedure/Surgeryoophorectomy to remove a disease ovary.
Treatment groups
300 Participants
are divided into 1 treatment groupGroup A: Use of high dose chemotherapyOther 1 intervention
Trial outcomes
Primary outcomes
1
CRYOPRESERVATION OF OVARIAN TISSUE FOR POTENTIAL IN VITRO MATURATION OR AUTOLOGOUS TRANSPLANTATION
Ovarian tissue cryopreservation Survival of tissue undergoing cryopreservation, thawing and maturation of immature eggs.
Time frame
6 months to a year post surgery, hormone testing will be performed to test ovarian function.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov