Health TrialsbyHealthPanel

CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related Arthropathies

ConditionsGoutChondrocalcinosisHydroxyapatite
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorLille Catholic University

About this trial

The objective of this research is to collect data to create an observatory of microcrystalline rheumatism (gout and calcium-crystal rheumatism) in patients treated at the Groupement des Hôpitaux de l'Institut Catholique de Lille, in order to better understand the disease and improve patient care, in particular with the help of medical imaging.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Diagnosis of gout according to American College of Rheumatology /European League Against Rheumatism (ACR/EULAR) 2015 criteria OR diagnosis of calcium pyrophosphate dihydrate crystal deposition disease (CPPD) based on EULAR 2011 recommendations OR diagnosis of hydroxyapatite crystal rheumatism (HCR) according to a typical clinical sequence and demonstration of compatible calcium deposits on imaging

patient who will benefit or has benefited from an ultrasound and/or DECT evaluation of microcrystalline deposits

clinical suspicion of microcrystalline rheumatism requiring further imaging to confirm the diagnosis

Disqualifiers

Refusal or contra-indication to perform ultrasound or dual energy scanning.

Patient's opposition to the use of his or her health data for research purposes

Patient under guardianship or curatorship

Pregnant woman

Trial population

Gout Chondrocalcinosis Hydroxyapatite

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Data collection

    Other intervention

    The following data will be collected by the physician: sociodemographic profile, clinical manifestations, comorbidities, laboratory tests,etc. Diagnostic performance of different imagery techniques, performance of crystal deposit quantification in ultrasound and Dual-energy computed tomography (DECT), link between co-morbidities and volume of baseline crystal deposits then during monitoring, link between co-morbidities (including cardiovascular events and new diagnoses of co-morbidity) and vascular baseline crystal deposits and during follow-up, link between microcrystalline rheumatism activity and the quantity of crystal deposits in baseline imaging and during follow-up, link between co-morbidities and the evolution of microcrystalline baseline rheumatism and then during follow-up, link between co-morbidities and the evolution of crystal deposition volumes, the concordance of the evaluation of uratic stocks and their evolution between the imagery means.

Treatment groups

1,000 Participants
are divided into 1 treatment group
Group A: Persons with crystal related arthropathies1 intervention

Trial outcomes

Primary outcomes

1

Diagnosis of microcrystalline rheumatism

Time frame
day 0
2

Weight

measured in Kg

Time frame
day 0
3

Height

measured in cm

Time frame
day 0
4

Index body mass

Time frame
day 0

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Lille Catholic University

Lead sponsor

Source ClinicalTrials.gov
Apply now