Health TrialsbyHealthPanel

Curcumin & Astaxanthin for Lowering Triglyceride Readings and Inflammation

ConditionTriglycerides
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-59
SponsorMedinutra LLC

About this trial

Two dietary supplements are each being compared to a placebo for the ability to help maintain triglycerides in the normal range. The subjects will be adult men and women with moderately high TG values. Serum triglycerides will be measured before and after 6 weeks of taking 1 capsule per day of either Longvida Curcumin, astaxanthin, or a placebo. A few side blood analysis will also be done. These measures are relevant to low level inflammation.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Triglyceride reading of 140-250 mg/dL

Age 21-59

Disqualifiers

Uncontrolled diabetes

Hypothyroidism or other hormonal problems that have not stabilized

Any liver diseases being actively treated

Cancer

Trial design

Design model

Parallel

Treatments tested in this trial

  • Curcumin (Longvida™)

    Dietary supplement

    1 capsule per day at a usual curcumin dose for this particular product (80 mg curcumin)

  • Half Dose Curcumin (Longvida™)

    Dietary supplement

    1 capsule per day at half the usual curcumin dose for this particular product (40 mg curcumin as the half dose)

  • Astaxanthin

    Dietary supplement

    1 capsule per day at a usual astaxanthin dose (12 mg)

  • Placebo Control

    Other intervention

    Subject will get 1 capsule per day of a small amount of cellulose

Treatment groups

64 Participants
are divided into 4 treatment groups
Group A: ControlPlacebo comparator 1 intervention
Group B: Regular dose curcuminExperimental treatment 1 intervention
Group C: Low dose curcuminExperimental treatment 1 intervention
Group D: AstaxanthinExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Trilgycerides

Serum triglyceride readings (mg/dL)

Time frame
Pre and post 6 week intervention

Secondary outcomes

1

Other blood lipids

Serum values for commonly measured blood measures for comparison purposes: total cholesterol (mg/dL, LDL cholesterol (mg/dL), and HDL cholesterol (mg/dL) These are not expected to be affected by the interventions except possibly a small rise in HDL cholesterol post-intervention in some groups.

Time frame
Before and after the 6 week intervention
2

Inflammation markers

As a secondary consideration, this study will assess 3 blood measures relevant to low level inflammation: serum c reactive protein (mg/dL), serum alanine aminotransferase (ALT-Units/L), and whole blood glutathione (mg/L)

Time frame
Measures will be from blood samples taken before and after the 6 week intervention.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Medinutra LLC

Lead sponsor

Source ClinicalTrials.gov
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