Current Status of Diagnosis and Treatment of Uroepithelial Carcinoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorThe First Affiliated Hospital of Xinxiang Medical College

About this trial

A cross-sectional study describing the current status of diagnosis and treatment of uroepithelial cancer in hospitals of different grades in Henan Province

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults ≥18 years of age (at enrollment)

Histologically confirmed uroepithelial carcinoma

Patients with newly diagnosed or completed radical uroepithelial carcinoma in the early stages of uroepithelial cancer/advanced unresectable or with distant metastases of urothelial carcinoma

Complete medical history information

Disqualifiers

Incomplete medical history and medical records

Trial population

Patients diagnosed with uroepithelial carcinoma attending multiple research center hospitals in Henan Province from January 1, 2023-December 31, 2023

Trial design

Design model

Case-only

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

400 Participants
are grouped into 2 trial groups
Group A: Diagnosis and management of patients with early stage resectable uroepithelial carcinoma
Group B: Diagnosis and management of patients with advanced unresectable uroepithelial cancer

Trial outcomes

Primary outcomes

1

Describing the diagnosis and treatment patterns of patients with early versus advanced uroepithelial carcinoma in different grades of hospitals in Henan Province

To describe the similarities and differences between the way patients with early and advanced uroepithelial cancer are diagnosed and treated in different levels of hospitals in Henan Province and the current guidelines for uroepithelial cancer.

Time frame
up to the patients enrolled,an average of 1 year

Secondary outcomes

1

Comparison of differences in diagnosis and treatment patterns between patients with early-stage and advanced uroepithelial carcinoma in county hospitals and different consultation departments of the same hospital in Henan province

The main purpose of this study is to compare the differences between the diagnosis and treatment modalities and guidelines for early and advanced uroepithelial cancer patients in Henan Province in county hospitals. It also compares the differences in treatment modalities between different departments in the same level of hospitals.

Time frame
up to the patients enrolled,an average of 1 year
2

Describing the pathology as well as genetic testing of patients with uroepithelial carcinoma in different grades of hospitals in Henan province

1. Proportion of different genes/proteins tested in patients with uroepithelial cancer (mutations in FGFR, HER2, HRR, ARID1A and CREBBP, TP53, CDKN2A and PD-L1 expression) 2. Proportion of early and advanced uroepithelial cancer patients with high expression/mutations of different genes and use of targeted therapies

Time frame
up to the patients enrolled,an average of 1 year

Other outcomes

Sponsors and contacts

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