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Decentralized Imaging by REmote Computer Tomography for Cerebral Infarct Thrombolysis

ConditionStroke
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital of North Norway

About this trial

The DIRECT-CT trial is designed to test the hypothesis that remote controlled CT scanning combined with real time audio-and video conference (AVC) guided assessment from an experienced hospital stroke team (tele-stroke) at decentralized medical centers (DMC) reduces time to intravenous thrombolytic treatment compared to the standard pathway.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Decentralized diagnostics and treatment

    Other intervention

    The intervention includes admittance to the DMC for initial diagnostic work up and acute treatment (if indicated). Paramedics examine the patient and assess stroke severity by NIHSS and G-FAST scoring overseen by a stroke physician at the local hospital through real time video conference. A remote controlled CT scan of the head is conducted, and the stroke team at the local hospital evaluates results and makes a treatment decision in real-time AVC. If treatment is indicated, this is administered by local personnel at the DMC before initiating transport to the local hospital or the comprehensive stroke center in case of LVO. Patients who are unable to reach the DMC prior to estimated admission time at their local hospital, will be treated at their local hospital as per standard pathway.

Treatment groups

52 Participants
are divided into 3 treatment groups
Group A: Intervention armExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions
Group C: Historical controlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Time from EMC notification to initiation IVT treatment

The time from Emergency Medical Communication notification to initiation intravenous thrombolysis treatment in eligible patients

Time frame
Day 0

Secondary outcomes

1

Time from admittance to initiation of IVT treatment (door-to-needle time)

Time from admittance to initiation of IVT treatment (door-to-needle time) in eligible patients

Time frame
Day 0
2

Time from admittance to start of blood pressure lowering medication in ICH patients

Time from admittance to start of blood pressure lowering medication in ICH patients patients

Time frame
Day 0
3

Proportion of AIS patients receiving IVT treatment (y/n)

Proportion of acute ischaemic stroke patients receiving IVT treatment (y/n)

Time frame
Day 0
4

Proportion of AIS patients receiving EVT treatment (y/n)

Proportion of acute ischaemic stroke patients receiving endovascular treatment

Time frame
Day 0

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital of North Norway

Lead sponsor

Helgelandssykehuset Hospital Trust

Collaborator

Nordlandssykehuset Hospital Trust

Collaborator

Finnmarkssykehuset HF

Collaborator

UiT The Arctic University of Norway

Collaborator

Innlandet Central Hospital HF, Lillehammer

Collaborator

Oslo University Hospital

Collaborator

Ringerike hospital HF, Hønefoss Norway

Collaborator

Source ClinicalTrials.gov
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