Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe Cleveland Clinic
About this trial
The purpose of this study is to learn how brain signals are related to freezing of gait (FOG) and balance problems in Parkinson's disease (PD) and to study how different deep brain stimulation (DBS) settings may affect these symptoms.
Eligibility criteria
Qualifiers
You have been diagnosed with Parkinson's disease
You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device
Your DBS settings have been stable for at least 3 months
You experience freezing of gait (sudden inability to move your feet when trying to walk)
Disqualifiers
You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis)
You have been diagnosed with dementia or have difficulty understanding the study or giving consent
You currently have alcohol or substance abuse problems
You have hearing or vision problems that would make it difficult to use a virtual reality headset
Trial design
Treatments tested in this trial
- Multiple Deep Brain Stimulation (DBS) Conditions
- Moving Overground in a Virtual Environment (MOVE)
- Cleveland Clinic Stair Ambulation and Functional Evaluation of Gait (SAFE-Gait)
Treatment groups
5 Participants
are divided into 1 treatment groupSponsors and collaborators
The Cleveland Clinic
Lead sponsor
Medtronic
Collaborator
Source ClinicalTrials.gov