Deep Learning-Assisted Ultrasonic Diagnosis and Localization of Testicular Appendix Torsion

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age1-18
SponsorYing Jiang

About this trial

Ultrasound data were both retrospectively and prospectively collected from the primary center and six other sub-centers. Combined with clinical diagnostic outcomes, the data labeling was completed by physicians with extensive clinical experience. In this study, ConvNeXtV2 was used as the classification network and YOLOv12 was adopted as the detection network.The retrospective dataset from the primary center was split into training, validation, and test subsets, on which the model was trained, validated, and tested respectively; additional validation was conducted on both retrospective and prospective datasets from the primary center and sub-centers.Meanwhile, four physicians were assigned to interpret the ultrasound data from the retrospective and prospective datasets from the primary center and sub-centers using two diagnostic methods-independent diagnosis and artificial intelligence (AI)-assisted diagnosis-and the diagnostic accuracy of these two approaches was further compared.By collecting and learning the treatment methods of patients in the primary center training set, predicting the treatment methods of patients in the sub-center datasets, and comparing the proportion of surgeries predicted by AI with the actual proportion of surgeries, the efficacy of the model was verified.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age ≤ 18 years old

Underwent ultrasound examination due to acute scrotal pain (≤ 24 hours)

Patients clinically diagnosed with testicular appendage torsion (TAT)

Disqualifiers

Poor ultrasound image quality (failure to identify testicular structures)

Incomplete clinical data (failure to confirm the diagnosis of testicular appendage torsion [TAT])

Trial population

Age ≤ 18 years old,underwent ultrasound examination due to acute scrotal pain (≤ 24 hours)

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

Not listed

Trial groups

2,000 Participants
are grouped into 4 trial groups
Group A: Testicular Appendix Torsion Group
Group B: Testicular Torsion Group
Group C: Epididymitis Group
Group D: Normal Group

Trial outcomes

Primary outcomes

1

Accuracy of deep-learning model verify four conditions:testicular appendage torsion;testicular torsion;epididymitis and normal condition

accuracy of deep-learning model verify four conditions:testicular appendage torsion;testicular torsion;epididymitis and normal condition

Time frame
From image input to result generation is expected to be 24 hours

Secondary outcomes

1

Number of Participants with Acute Scrotal Pain

Time frame
From enrollment begin to the end is expected to be 5 months
2

The accuracy rate of clinicians in diagnosing and localizing testicular appendix torsion

Time frame
From the begin of Clinicians diagnose and locate to the end is expected to be 15 days
3

The accuracy rate of the Deep learning model in predicting the treatment modality for testicular appendix torsion,conservative treatment or surgery

Time frame
From the begin of the prediction of treatment for testicular appendix torsion by Deep learning model to the end is expected to be 24 hours

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ying Jiang

Lead sponsor

The Children's Hospital of Zhejiang University School of Medicine

Sponsor institution

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