Deep Learning Model for Predicting a Peripheral Venous Waveform-based Pulse Pressure Variation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-80
SponsorSeoul National University Bundang Hospital

About this trial

Pulse pressure variation is a monitoring index that indicates the response to fluid therapy in patients receiving mechanical ventilation, and is used as a reference for patients with unstable hemodynamic conditions. However, it is invasive because it requires arterial puncture to collect it. In a previous study by the investigators, the investigators developed and verified an artificial intelligence model that predicts stroke volume variation, in real time using only the central venous pressure waveform. However, since a large vein such as the jugular vein must be punctured to collect the central venous pressure waveform, it is still invasive, and its clinical utility is low. Therefore, in this study, the investigators collected waveforms from peripheral veins that are less invasive and can be a wide range of applications because all surgical patients have them. The investigators aimed to develop and verify an artificial intelligence model that predicts pulse pressure variation obtained from peripheral venous waveforms .

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients who voluntarily agreed and signed the written informed consent form before participating in this study

Adult aged 19 years or older

American Society of Anesthesiologists physical class (ASA) 1-3

Patients scheduled for elective hepatectomy under general anesthesia

Disqualifiers

Patients with abnormal findings on electrocardiogram before surgery

Patients who cannot undergo peripheral venous puncture

Trial population

Patients scheduled for elective hepatectomy under general anesthesia

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • peripheral waveform collection

    Other intervention

    The peripheral venous pressure waveform is collected by connecting a pressure transducer that is currently in use to the placed central venous line. In addition, the pulse pressure variation or stroke volume variation value that can be obtained from the arterial catheter. This extracts the medical records and bio-signal information of the subjects registered through the previously approved 'Establishment of a Bio-signal and Clinical Information Registry for the Development of Patient Monitoring Algorithm' study (B-2202-738-401).

Treatment groups

150 Participants
are divided into 1 treatment group
Group A: Peripheral waveform collection group1 intervention

Trial outcomes

Primary outcomes

1

Pulse pressure variation

from arterial waveform

Time frame
intraoperative period

Secondary outcomes

Other outcomes

Sponsors and contacts

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