Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia
ConditionDental Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-18
SponsorUniversity Hospital, Toulouse
About this trial
The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received.
The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
A patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome
Patient or legal representative not opposed to participating in this research.
Disqualifiers
Inability to understand and respond to quality of life questionnaires
Trial population
Children aged 12 to 18 years
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
Questionnaires
Other intervention* " Psychosocial Impact of Dental Aesthetics Questionnaire " PMID 24280547 * " Orofacial Esthetic Scale " PMID 30856637 * " Orofacial Esthetic Scale " PMID 34231057 * A photograph of the patient's smile will be sent to 2 dentists who will also assess the presence or absence of dental dyschromia.
Treatment groups
120 Participants
are divided into 1 treatment groupGroup A: Dental Dyschromia in Hyperbilirubinemia Patients1 intervention
Trial outcomes
Primary outcomes
1
Prevalence of dental dyschromia
presence of dyschromia or not evaluated by 2 investigators
Time frame
from birth to study completion, a maximum of 19 yearsSecondary outcomes
1
Presence or absence of dental dyschromia
Presence or absence of dental dyschromia based on various variables such as bilirubin levels or the duration of hyperbilirubinemia.
Time frame
through study completion, an average of 18 monthsOther outcomes
1
Quality of life score by patient group
Assess the quality of life score based on the patient's group classification
Time frame
through study completion, an average of 18 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov