Detachable Clip-assisted Endoscopic Cyanoacrylate Injection in the Treatment of Gastric Varices

ConditionGastric Varices Bleeding

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-80

SponsorYu Chang

About this trial

A single-arm exploratory clinical study design was used to evaluate the safety and efficacy of a "modified sandwich injection" of tissue glue assisted by a detachable clip for the treatment of gastric varicose veins.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

The subject voluntarily signs the informed consent for this experiment; According to clinical manifestation, laboratory examination, imaging examination, or liver biopsy in the diagnosis of liver cirrhosis patients; The endoscopy diagnosed gastric varices (gastroesophageal varices, gastroesophageal varices type 2 or type 1 isolated gastric varices type 1); High risk of gastric varices or has a history of gastric varices bleeding. The initial fluid resuscitation patients before or after the recovery hemodynamic stability; The age of 18 years old or more.

Disqualifiers

< 18 years old; Regional portal hypertension; Always have a liver transplant, via the jugular intrahepatic portal vein system bypass or splenectomy combined varices cut-out art history; A concurrent hepatorenal syndrome and/or multiple organ failure; Significant impact on survival of malignant tumor; Pregnancy or lactation; A known allergy to iodine.

Trial design

Design model

Single group

Treatments tested in this trial

Detachable Clip
Other intervention
After the varicose vessels basically disappeared under the endoscope, the removable titanium clamp was removed

Treatment groups

6 Participants

are divided into 1 treatment group

Group A: Detachable Clip-assistedExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Rebleeding rate at 6 weeks after treatment for gastric fundus varicose veins in cirrhosis

Time frame

6 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Yu Chang

Lead sponsor

Nanjing University of Traditional Chinese Medicine

Sponsor institution

Source ClinicalTrials.gov

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