Detection of Microplastics in Patients With Periodontitis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSigmund Freud PrivatUniversitat

About this trial

Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18 and over

Gender: Female / male / diverse

Patients

who have been diagnosed with stage III and IV periodontitis.

Disqualifiers

Patients

who have already been treated for periodontitis

who have already undergone/begun periodontitis treatment

Trial population

Patients with periodontitis, stage 3 or 4, with a full mouth probing score at the Department of Periodontology, Dental Clinics, Sigmund Freud University, Vienna, Austria

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

25 Participants
are grouped into 1 trial group
Group A: patients with periodontitis, stage 3 or 4

Trial outcomes

Primary outcomes

1

Microplastics

number of patients with periodontitis with microplastics in periodontal pockets, quantification of microplastic particles in periodontal pockets, qualitative analysis of microplastic

Time frame
one year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: