Detection of Muscle Quality in Children - Protocol for a Validation Study
ConditionUltrasonography
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age10-14
SponsorCharles University, Czech Republic
About this trial
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese, and trained young athletes. The main questions it aims to answer are:
Can EI reliably and accurately measure muscle quality in children when validated against gold-standard techniques like DXA and isokinetic dynamometry? What are the age-, sex-, and fitness-specific benchmarks for EI to differentiate between normal and pathological muscle quality?
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Acute illnesses
Chronic or acute diseases of the endocrine or musculoskeletal systems
Post-traumatic conditions
Trial population
Sixty boys and sixty girls aged 10-14 years, evenly distributed as follows: normal-weight children, trained young athletes (≥3 training sessions per week), and obese children according to BMI
Trial design
Design model
Other
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Echo intensity of the vastus lateralis (VL) and rectus femoris (RF) muscles
Echo intensity will be measured by greyscale analysis derivered from ultrasound imaging.
Time frame
Through study completion, an average of 1 yearSecondary outcomes
1
Skeletal Muscle Mass
Measured using DXA (Horizon DXA platform, Hologic)
Time frame
Through study completion, an average of 1 year2
Muscle Strength
Assessed via isokinetic and isometric knee extensor strength using a Humac Norm isokinetic dynamometer
Time frame
Through study completion, an average of 1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: