Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

The aim of the REBELLE cohort - bio-collection is to collect samples from patients with Chronic Lymphocytic Leukemia candidates or those exposed to BTK degraders to evaluate the mechanisms of resistance to these new molecules. To do this, an additional blood or bone marrow sample to those planned in the context of patient care or a residual lymph node biopsy sample will be collected after signing consent.

Eligibility criteria

Qualifiers

Patient with CLL candidates ou exposed to BTKd

Patient who has provided informed consent to participate in the study.

Patient covered by a social security health insurance plan

Disqualifiers

Minor patients.

Adults under guardianship.

Protected persons.

Trial design

Treatments tested in this trial

  • Non-Interventional Sample Collection and Analysis

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators