Determining Individualized Cancer Therapy in Pancreatic Cancer
ConditionPancreatic Neoplasms
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMedical College of Wisconsin
About this trial
This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥18 years.
Pathologically confirmed pancreatic cancer.
Ability to understand a written informed consent document and the willingness to sign it
Disqualifiers
Age <18 years.
Primary cancer diagnosis other than pancreatic cancer.
Trial population
The study population will be selected from individuals seeking treatment for pancreatic cancer who have had next generation genomic sequencing of their tumors.
Trial design
Design model
Cohort
Time perspective
Other
Treatments tested in this trial
Targeted Therapy
Other interventionApproved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Number of Subjects Receiving Targeted Therapy
This measure is the number of study subject's whose treating physician prescribes and subsequently receives the therapeutic recommendation of the Molecular Tumor Board.
Time frame
5 yearsSponsors and contacts
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Source ClinicalTrials.gov