Developing a New EEG Method for the Early Diagnosis of Dementia
ConditionDementia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSheffield Teaching Hospitals NHS Foundation Trust
About this trial
This is a non-invasive study investigating whether EEG, which is used in routine clinical care can be useful in diagnosing dementia. Novel in house developed software will analyse EEG data for this purpose from people with Alzheimer's disease and healthy volunteers.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Significant vascular change on neuro-imaging (Fazekas grading of white matter change >2) (Fazekas et al., 2002).
Clinical history of stroke, Parkinsonism, epilepsy or other neurological disorder. (e.g. severe auditory, visual, language or motor impairment)
Moderate to severe dementia (defined by research team but we wouldn't expect those with a mini mental state exam [MMSE] ≤ 18 to be able to participate)
Severe current mental health disorder (depression, psychosis).
Trial population
Clinical diagnosis of possible or probable AD (according to revised diagnostic criteria (McKhann et al., 2011, Dubois et al., 2007)
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
128 Participants
are grouped into 2 trial groupsGroup A: People with Alzheimer's disease
Group B: Healthy volunteers
Trial outcomes
Primary outcomes
1
Significant spatiotemporal measurements from EEG
EEG data analysis
Time frame
12 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov