Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-89
SponsorAdventHealth Translational Research Institute

About this trial

The purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Male or female

Age 12 - 89

Healthy (self assessed)

Weight under 350lbs

Disqualifiers

Have internal metal medical devices, including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws, metal fragments in your eye, or non-removable jewelry such as rings.

Are unwilling or unable to complete the imaging procedures for the duration of the MRI scan due to claustrophobia or other reason.

Serious mental illness that might preclude subject's ability to comply with study treatment

Life expectancy of less than 1 year

Trial population

A healthy individual, who is willing and able to undergo MR imaging and spectroscopy for up to two hours at a time

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

  • To evaluate the reproducibility of acquiring multi-nuclear data on a new 3T Philips Magnet

    Other intervention

    Outside standard MR instrumentation there will be no interventions.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Whole body fat quantification

Time frame
1 hour

Secondary outcomes

1

Fat Microstructure

A high resolution image of the structure of fat tissue.

Time frame
1 hour

Other outcomes

1

Flow high resolution imaging

Image of the movement of fluids in the area being imaged.

Time frame
1 hour
2

Intramyocellular fat quantification

Use to determine the amount and types of fat inside muscle and liver.

Time frame
45 minutes
3

Intrahepatic fat quantification

A measure of the amount of fat in the liver.

Time frame
45 minutes

Sponsors and contacts

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