Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna

About this trial

The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS).

The main questions it aims to answer are:

* is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results? * is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease?

Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age over 18

suspect of soft tissue sarcoma with a indication for surgical treatment

suspect of bone cancer tumor with a indication for surgical treatment

To give informed consent

Disqualifiers

simultaneous cancer or history of cancer in the last 5 years

acute or chronic serious conditions that could

renal failure without dialysis

history of allergy to a paramagnetic contrast agent

Trial population

The study population consists in participants with a suspect of soft tissue sarcoma or bone cancer that are followed at Radiology Department of IRCCS Azienda Ospedaliero-Universitaria hospital in the city of Bologna.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Positive Predictive Value (PPV)

It is the ratio of patients truly diagnosed as positive to all those who had positive test results (including healthy subjects who were incorrectly diagnosed as patient).

Time frame
From enrollment to the end of treatment at 2 years
2

Negative Predictive Value (NPV)

It is the ratio of subjects truly diagnosed as negative to all those who had negative test results (including patients who were incorrectly diagnosed as healthy).

Time frame
From enrollment to the end of treatment at 2 years

Secondary outcomes

Other outcomes

Sponsors and contacts

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