Research into cancer patients has shown that quality of life is significantly altered by the disease and its associated treatments and is also reported to be a predictor of significant emotional distress. Blood cancer patients are among those most affected in terms of quality of life, facing stem cell transplantation after high-dose chemotherapy, a treatment that is recognized as one of the most stressful of cancer therapy, due to the many adverse effects, including pain, and the uncertainty linked to the fear of graft failure. Hypnosis interventions are proving effective in treating common side effects: nausea, pain, fatigue, anxiety, depressive symptoms and improving overall quality of life, and other interventions, based on virtual reality, have shown promising effects on patients' distress and acute pain. The aim of this study is to evaluate the effects of an intervention program combining hypnosis and virtual reality in assisting myeloma and lymphoma patients during stem cell transplantation, with a view to improving their quality of life during this period. The project aims to assess the validity of the intervention, and to evaluate the effects of the intervention on patients' anxiety, pain and fatigue during transplantation. The validity of the intervention will be measured by a questionnaire assessing the relevance and acceptability of the intervention, expected effects, and practical implementation. Socio-demographic and clinical data will be collected from patients, including axiety, pain, fatigue and quality of life, studied at pre (one week after transplantation) and post (one month after transplantation) intervnention, and at follow-up (three month after transplantation).
Being 18 years of age or older
Suffering from multiple myeloma or lymphoma eligible for transplant
Understanding French
Deafness
Blindness
Confusion or psychopathological disorders (for example, schizophrenia) that may impair communication
Parallel
Virtual Reality Hypnosis
DeviceAn intervention program (VRH) that combines VR and hypnosis; Can use it whenever and how much they want. It contains 200 landscapes in VR and 4 different VRH sessions
VRH : Beach
DeviceHypnosis session with a VR immersion at the beach; one accompanied session
VRH : Forest
DeviceHypnosis session with a VR immersion in forests; one accompanied session
VRH : MagicHand
DeviceHypnosis session with a VR immersion with techniques to reduce pain; one accompanied session
VRH : SecurityProtection
DeviceHypnosis session with a VR immersion with techniques to reduce anxiety; one accompanied session
Anxiety and depression
Anxiety-depression will be measured using the Hospital anxiety and depression scale (HADS), a scale validated in French for cancer. This scale is made up of 14 items: 7 items determine the degree of anxiety and the other 7, the degree of depression. The score of each subscale is calculated by summing the score of each item, which varies between 0 and 3, so that each subscale can reach a maximum score of 21
Level of pain
Pain will be assessed with the Brief Pain Inventory. This scale is made of 8 items on a 10-points Lickert scale (0=no pain, 10=worst pain) assessing severity of pain, impact of pain on daily function, location of pain, pain medications and amount of pain relief in the past 24 hours or the past week.
Level of quality of life
Quality of life will be assessed by FACT-BMT, which comprises 50 items in 5 subscales : Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Bone Marrow Transplantation Subscale scored on a 5-points Likert scale (0=not at all, 4=very much).
Absorption
Absorption will be measured using a eleven-level Visual Numerical Scales (VNS) (minimum 0=no absoption at all, maximum 10=totally absorbed)
Dissociation
Dissociation will be measured using a eleven-level Visual Numerical Scales (VNS) (minimum 0=no dissociation, maximum 10=fully dissociated).
Level of expectation and satisfaction
Level of expectation and satisfaction will be assessed using a five-level Visual Numerical Scales (VNS) (1 = "not at all satisfied", 5 = "very satisfied") and semi-structured interviews
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