Health TrialsbyHealthPanel

Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects

ConditionsMRISequence OptimizationPhysiological Measurement
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Grenoble

About this trial

IRMaGe is a Joint Service Unit (UMS) which provides users of brain exploration equipment (clinical MRI and preclinical, TMS, EEG, NIRS and metabolomics). The methods available on this equipment are intended to evolve according to the most recent discoveries and this protocol aims to frame the developments necessary around clinical MRI for IRMaGe can continue to offer tools at the cutting edge of technology.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Participants with normal or corrected vision

Participants affiliated to a social security scheme or beneficiaries of such a scheme

Participants with French as their mother tongue

Participants who have given the signed informed consent before carrying out any procedure related to the study.

Disqualifiers

metallic glitter in the eyes

retinal operation

claustrophobia

wearer of pacemaker or cardiac defribrillator or vascular clip or prosthesis cardiac or insulin pump or implanted device to deliver medication or hearing implant or prosthesis or vascular shunt or paragraph or screws, plate metal or tattoo or piercing or implanted metal object or lead shot hunt

Trial design

Design model

Single group

Treatments tested in this trial

  • MRI Protocol

    Device

    Eye-tracker Eyelink (eye movements) BIOPAC : (electrodermal resistance) INVIVO Precess : breathing, arterial pressure, pulse, * NIRS Oxymon artinis medical system * tES (transcranial electrical stimulation, Neuroelectrics)

Treatment groups

600 Participants
are divided into 1 treatment group
Group A: MRI protocolExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Diffusion Tensor Imaging Images

DTi sequences on IRM Achieva 3.0T dStream Philips

Time frame
1 to 3 hours
2

BOLD Signal

EPI sequences during cognitive protocol on IRM Achieva 3.0T dStream Philips

Time frame
1 to 3 Hours
3

Anatomical Images

Anatomical MR sequences on IRM Achieva 3.0T dStream Philips

Time frame
1 to 3 hours

Secondary outcomes

1

Eye movements

Acquired by using eye-tracker (Eye-tracker Eyelink) breathing arteries pressure electrodermal conductance

Time frame
During MRI session
2

Electrodermal resistance

Acquired on BIOPAC device allowing physiological measurements

Time frame
During MRI session
3

Blood Pressure/pulse/Breathing

Acquired on INVIVO Precess

Time frame
During MRI session
4

Near-infrared spectroscopy (NIRS) : Hb OHb concentration measurement

Acquired with NIRS Oxymon artinis medical system

Time frame
During MRI session

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital, Grenoble

Lead sponsor

Source ClinicalTrials.gov
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