Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation
ConditionValvular Cardiac Surgeries
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-50
SponsorEgymedicalpedia
About this trial
Postoperative sedation is an essential component in recovery of the patient undergoing cardiac surgery. It facilitates the patient's unawareness of the environment as well as reduce the discomfort and anxiety caused by surgery, intubation, mechanical ventilation, suction, and physiotherapy.
Despite the advances in anesthesia and surgical techniques, the duration of mechanical ventilation (MV) may be prolonged after cardiac surgery, due to the classic high-dose narcotic-based cardiac anesthesia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Patient refusal.
Emergent valve cardiac surgeries.
Patients with known hypersensitivity to study drugs.
History of uncontrolled diabetes or hypertension.
Trial design
Design model
Parallel
Treatments tested in this trial
Dexmedetomidine
Drugto investigate the postoperative analgesic-sedative effect of dexmedetomidine versus fentanyl-midazolam to achieve fast-track extubation after adult valvular cardiac surgeries.
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: Dexmedetomidine GroupExperimental treatment 1 intervention
Group B: Fentanyl GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Pain Relieve
Assessment of the pain post-operatively in patients with pain score by VAS as : Total scores vary from 0 to 10 in this method, with a higher score indicating more severe pain
Time frame
2 hours post operativeSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov