Diabetes Prevention AI: Enhancing Prevention Strategies Using Personalized Nutrition and Fitness Coaching for the Next Generation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorEmory University

About this trial

This study is testing an artificial intelligence (AI) chatbot designed to help adults at risk for type 2 diabetes adopt healthier lifestyles. The chatbot provides personalized and culturally tailored guidance on nutrition, physical activity, resistance training, and goal setting. About 30 adults aged 18 to 55 years will use the chatbot for 6 weeks and provide feedback through surveys and interviews.

Researchers will evaluate whether the chatbot is easy to use, helpful, and trustworthy, and whether data about changes in health behaviors can be feasibly collected, in order to inform larger future studies to improve diabetes prevention.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

HbA1C of 5.7-6.4%

BMI of 18.5 - 24.9 kg/m²

Fasting plasma glucose 100 - 125 mg/dL

Family history of type 2 diabetes in first-degree relatives (parents, siblings, or children)

Disqualifiers

Are diagnosed with type 1 or type 2 diabetics

Have uncontrolled hypertension (higher than 160/100 mmHg)

Have cardiovascular disease

Are pregnant or planning to be pregnant

Trial design

Design model

Single group

Treatments tested in this trial

  • AI-Powered Diabetes Prevention Chatbot

    Behavioral

    Participants will use a generative AI chatbot designed to provide personalized, evidence-based diabetes prevention support. The chatbot delivers culturally tailored nutrition and physical activity recommendations, with an emphasis on high-protein dietary strategies, resistance training, goal setting, motivational support, and healthy lifestyle behaviors. Participants will be encouraged to interact with the chatbot at least three times per week during the 6-week study period. Recommendations are generated using expert-validated diabetes prevention content and personalized according to participant characteristics and preferences.

Treatment groups

30 Participants
are divided into 1 treatment group
Group A: AI-Powered Diabetes Prevention ChatbotExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Feasibility and Acceptability: Task completion rate

The proportion of recommended chatbot activities, goals, or behavioral tasks completed by participants during the 6-week intervention period, as assessed through chatbot analytics. This measure will be used to evaluate participant engagement and adherence to chatbot-delivered recommendations.

Time frame
Baseline, 6 weeks
2

Feasibility and Acceptability: Conversation length

Average number of messages exchanged between participants and the AI chatbot during each interaction session over the study period. Conversation length will be obtained from chatbot analytics and used as an indicator of participant engagement with the intervention. Longer conversations may reflect greater interaction with chatbot-delivered nutrition, physical activity, and lifestyle coaching content

Time frame
Baseline, 6 weeks

Secondary outcomes

1

Feasibility: Body Mass Index (BMI)

Proportion of participants for whom self-reported body mass index (BMI, kg/m²) is successfully collected at baseline and at the end of the 6-week intervention period. BMI will be calculated using participant-reported height and weight collected through study surveys.

Time frame
Baseline, 6 weeks
2

Feasibility: Physical Activity Behaviors

Proportion of participants for whom self-reported physical activity behaviors, including engagement in resistance training and overall activity levels, will be successfully collected through study questionnaires and chatbot interaction data.

Time frame
Baseline, 6 weeks
3

Feasibility: Dietary Behaviors

Proportion of participants for whom self-reported dietary intake and nutrition-related behaviors, including the adoption of higher-protein dietary practices and other healthy eating behaviors promoted by the chatbot intervention, are successfully collected. Data will be collected through participant surveys and chatbot interaction records.

Time frame
Baseline, 6 weeks
4

Feasibility: Behavioral Intention for Diabetes Prevention

Proportion of participants with successfully recorded self-reported intention and readiness to engage in healthy lifestyle behaviors for diabetes prevention, including dietary modifications and physical activity, as assessed through study questionnaires

Time frame
Baseline, 6 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Emory University

Lead sponsor

Georgia Center for Diabetes Translation Research

Collaborator

This trial is not recruiting at the moment. You can still explore other options: