Diagnostic Value of Next-Generation Sequencing Analysis in Biliary Tract Tumours
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
About this trial
The aim of this study is to identify a dysplasia- and CCA-specific NGS panel to increase the diagnostic sensitivity of histological and/or cytological examination of biliary tract stenosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Availability of enough tissue for histological and NGS analysis (at least 20 ng DNA).
Age greater than/equal to 18 years.
Disqualifiers
None
Trial design
Design model
Single group
Treatments tested in this trial
NGS
Diagnostic testTissue samples will be processed and analysed at the U.O. of Pathological Anatomy
Treatment groups
50 Participants
are divided into 1 treatment groupGroup A: Patients undergoing biliary tract resectionExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Identification of an NGS panel specific to dysplasia and CCA
Ratio between the number of cases identified with NGS panel and the number of cases identified with standard of care
Time frame
During enrollment period, up to 30 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov