Diaphragm Response in Elderly for Acute Monitoring
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age75+
SponsorCentre Hospitalier de Bethune
About this trial
Acute dyspnea is a common cause of emergency department admissions among elderly patients. Acute respiratory failure is often multifactorial and requires rapid and reliable evaluation. Currently, management relies on clinical, biological, and radiological assessments, but diaphragmatic ultrasound could provide an additional tool for real-time respiratory function evaluation. This study aims to integrate this non-invasive technology into the initial assessment of patients to improve care pathways. Hypothesis : Diaphragmatic ultrasound enables reliable assessment of respiratory function and can predict the need for mechanical ventilation.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged ≥ 75 years
Emergency admission for acute dyspnea
Requiring an emergency ultrsoung.
Disqualifiers
Acute respiratory distress requiring immediate invasive or non-invasive ventilation
Respiratory rate ≥ 25 breaths/min, and/or SpO2 ≤ 90% on room air, and/or PaO2 ≤ 60 mmHg
Known diaphragmatic paralysis
Patients with degenerative neuromuscular disease
Trial population
Patients Aged 75 and Over Admitted to the Emergency Department for Acute Dyspnea
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Occurrence of a severe acute respiratory event within 7 days of admission
* Placement on invasive mechanical ventilation (intubation) or non invasive ventilation (NIV, high-flow oxygen therapy), * Respiratory death, confirmed by an independent adjudication committee blinded to the ultrasound results. Explanatory variable: The presence of impaired diaphragmatic function at admission will be defined by: * a Tdi (tele-inspiratory thickness) \<10%, and/or * a diaphragmatic excursion \<10 mm.
Time frame
WITHIN 7 DAYS OF ADMISSIONSecondary outcomes
1
Measurement of diaphragmatic excursion AND Etiology of acute dyspnea
To study the association between diaphragmatic excursion curve parameters (EDR, inspiratory time, expiratory time, etc.) and the etiology of acute dyspnea in patients aged 75 years and older admitted for acute dyspnea
Time frame
within 7 days2
To evaluate the contribution of diaphragmatic ultrasound to the NEWS2 score performed on admission in predicting the occurrence of acute respiratory distress within 7 days.
The discriminatory power of the NEWS2 score in predicting the occurrence of acute respiratory distress, the discriminatory power of the NEWS2 score combined with impaired diaphragmatic function on admission ultrasound. NEWS 2 : The higher the score, the greater the risk of clinical deterioration. 0-4 : low risk Score of 3 in any individual parameter : low-medium 5-6 : moderate risk \> or = 7 : high risk
Time frame
within 7 daysSponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: