Dietary Patterns, Inflammation, Zinc Status, and Body Composition in Multi-Ethnic Women of Reproductive Age in Jakarta
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age19-49
SponsorIndonesia University
About this trial
This study aims to determine the relationship between dietary patterns and hair zinc levels with body composition, tumor necrosis factor alpha (TNF-α), and blood pressure in women of reproductive age from different ethnic backgrounds in Jakarta, Indonesia (specifically Minangkabau, Sundanese, Javanese, Betawi, and Chinese). Participants are assessed once through dietary assessment, anthropometric measurements, and biological sample collection.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Women aged 19-49 years
Residing in Jakarta for at least 6 months
Currently menstruating (not menopausal)
From Minangkabau, Sundanese, Javanese, Betawi, or Chinese ethnicity
Disqualifiers
History of chronic diseases (e.g., diabetes, cardiovascular disease, cancer)
Currently on a medically prescribed diet or taking medication affecting nutrient status
Any condition interfering with accurate body composition measurement
Trial population
Women of reproductive age (19-49 years) living in Jakarta, Indonesia, from five major ethnic groups (Minangkabau, Sundanese, Javanese, Betawi, and Chinese), recruited from community settings.
Trial design
Design model
Case-only
Time perspective
Cross-sectional
Treatments tested in this trial
Not applicable- observational study
Other interventionThis is an observational study; no interventions are administered to participants.
Treatment groups
188 Participants
are divided into 1 treatment groupGroup A: Women of Reproductive Age (WRA) Participants1 intervention
Trial outcomes
Primary outcomes
1
Dietary Zinc Intake
Average daily zinc intake (mg/day) will be assessed using two dietary assessment methods: a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) and multiple-day Food Records. For women aged 19 to 49 years, the Recommended Dietary Allowance (RDA) is 8 mg/day, the Estimated Average Requirement (EAR) is 6.8 mg/day, and the Tolerable Upper Intake Level (UL) is 40 mg/day. Higher or lower values will be interpreted relative to these reference standards.
Time frame
At baseline (single assessment)2
Diet Quality Assessed by HEI-2020
The Healthy Eating Index-2020 (HEI-2020) is a measure of diet quality that assesses conformance to the 2020-2025 Dietary Guidelines for Americans. The score ranges from 0 to 100, with higher scores indicating better adherence and higher diet quality.
Time frame
Baseline (cross-sectional assessment at enrollment)3
Planetary Health Diet Index (PHDI)
The Planetary Health Diet (PHD), proposed by the EAT-Lancet Commission, is a dietary pattern designed to promote human health and environmental sustainability. The Planetary Health Diet Index (PHDI) is a scoring system (range: 0-150) that measures adherence to the PHD, with higher scores indicating greater adherence.
Time frame
Baseline (cross-sectional data collection)4
Ultra-Processed Food (UPF) intake
UPF intake will be estimated using the NOVA classification, expressed as percentage of total energy intake (%TEI). Higher percentages indicate worse outcome (poorer diet quality due to higher UPF intake).
Time frame
Baseline (cross-sectional data collection)Secondary outcomes
1
Inflammatory Biomarker Levels (TNF-α in Serum)
Serum TNF-α measured as a marker of inflammation, assessed in approximately 30% of total participants (sub-sample)
Time frame
At baseline (single assessment)Sponsors and contacts
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Source ClinicalTrials.gov