Dietary Wild Blueberries and Joint Health
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-75
SponsorUniversity of Nevada, Las Vegas
About this trial
The goal of this proposed study is to examine the effects of dietary wild blueberries on gut microbiome, serum markers of inflammation, and joint function in adults. Each participant will consume 25g freeze-dried blueberries or matched placebo powder for 12 weeks, with a 2-week washout phase between.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults with documented multi-joint/knee arthritis
Disqualifiers
inability to give informed consent
pregnancy or lactation
planned knee replacement surgery
allergy or contraindication to berries
Trial design
Design model
Crossover
Treatments tested in this trial
Wild blueberry
Dietary supplementFreeze-dried wild blueberry powder 25g/day
Placebo
Dietary supplementPlacebo powder matched for calories and no polyphenols
Treatment groups
50 Participants
are divided into 2 treatment groupsGroup A: Wild blueberriesExperimental treatment 1 intervention
Group B: PlaceboPlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Serum biomarkers of joint function
Serum biomarkers of inflammation and cartilage degradation will be measured in the wild blueberry and placebo groups and compared for outcomes. Pain scores will also be measured using self-reported questionnaires.
Time frame
12 weeksSecondary outcomes
1
Gut microbiome
Time frame
12 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Nevada, Las Vegas
Lead sponsor
Oklahoma Medical Research Foundation
Collaborator
Source ClinicalTrials.gov