Different Injection Speed on Local Anaesthetic Spread of ESPB

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNanjing First Hospital, Nanjing Medical University

About this trial

The aim of this clinical trial is to investigate the effect of different injection speeds on the spread of local anesthetic during ultrasound-guided erector spinae plane block (ESPB) in patients undergoing CT-guided lung nodule localization. The primary question addressed is whether a high injection speed (30 ml delivered within 30 seconds) produces a different local anesthetic distribution compared with a lower injection speed (30 ml delivered within 180 seconds).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

aged 18-80 years

BMI 18-30 kg/m²

ASA classification I-III

Disqualifiers

Allergy to the study drug or to local anesthetics

History of opioid abuse

Previous infection at the ESPB or PVB puncture site

Peripheral neuropathy

Trial design

Design model

Parallel

Treatments tested in this trial

  • injection speed

    Procedure/Surgery

    Patients undergoing CT-guided lung nodule localization were selected for the study, and ultrasound-guided erector spinae plane block was performed before surgery with different injection speed.

Treatment groups

74 Participants
are divided into 2 treatment groups
Group A: Group COther 1 intervention
Group B: Group SExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Spread of local anesthetic into the paravertebral space

Observation of local anesthetic spread into the paravertebral space with CT by a researcher who was blinded to group allocation

Time frame
30 minutes after completion of the ESPB block

Secondary outcomes

1

Diffusion of local anesthetic into intercostal space

The Incidence and thoracic level of local anesthetics to intercostal space was observed with CT by a researcher who was blinded to group allocation.

Time frame
30 minutes after completion of the block
2

Diffusion of local anesthetic into the epidural space

Incidence and segment of local anesthetic spread into the epidural was assessed by a researcher who was blinded to group allocationTime Frame: 30 minute after completion of the block

Time frame
30 minutes after completion of the block
3

Diffusion of local anesthetic into the neural foramina

Incidence and segment of local anesthetic spread into the neural foramina was assessed by a researcher who was blinded to group allocationTime Frame: 30 minute after completion of the block

Time frame
30 minutes after completion of the block
4

Cephalocaudal spread of local anesthetic

Observation of local anesthetic spread cephalocaudally

Time frame
30 minutes after completion of the block

Other outcomes

Sponsors and contacts

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