Digestive Biobank for Exploring Microbiota-host Interactions

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

Constitution of a biobank of tissues, whole blood and plasma samples and stools to identify markers associated with treatment response, postoperative morbidity including neuro-cognitive and mood complications and prognosis of Inflammatory Bowel disease or colorectal cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Ulcerative colitis, Crohn's disease or colorectal disease

Digestive resection with useless tissue available

Information consent signed

Disqualifiers

None

Trial population

Patients older than 18 years-old. With an Ulcerative colitis, Crohn's Disease or colorectal cancer Operated in the Departement of digestive surgery of Saint-Antoine Hospital After signature of the information consent

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

500 Participants
are grouped into 1 trial group
Group A: digestive cancer or IBD

Trial outcomes

Primary outcomes

1

Relation between biological parameters and outcomes of digestive disease (IBD, CRC)

identify relations between serumon response to treatment, postoperative outcomes including neuro-cognitive and mood complications and prognosis.

Time frame
up to 12 months after the incusion

Secondary outcomes

1

Relation between biological parameters and outcomes of digestive disease (IBD, CRC)

identify relations between plasma on response to treatment, postoperative outcomes including neuro-cognitive and mood complications and prognosis.

Time frame
up to 12 months after the incusion
2

Relation between biological parameters and outcomes of digestive disease (IBD, CRC)

identify relations between DNA on response to treatment, postoperative outcomes including neuro-cognitive and mood complications and prognosis.

Time frame
up to 12 months after the incusion
3

Relation between biological parameters and outcomes of digestive disease (IBD, CRC)

identify relations between faeces) on response to treatment, postoperative outcomes including neuro-cognitive and mood complications and prognosis.

Time frame
up to 12 months after the incusion
4

Exploratory study on the physiopathology of host-microbiota interactions to determinate the occurrence of intestinal and extra-intestinal complications

genetic polymorphisms, serum markers, intestinal microbiota markers to determining the occurrence of intestinal and extra-intestinal complications

Time frame
up to two months after the incusion

Other outcomes

Sponsors and contacts

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