About this trial
The goal of this clinical trial is to develop and learn if a digitally delivered brain health intervention (DiSaB) can help improve cognitive, physical and psychosocial health in middle-aged adults with chronic conditions at-risk for cognitive decline. The clinical trial also aims to find out the push and pull factors of implementing the intervention in primary care settings. The main questions it aims to answer are:
1. Does the DiSaB intervention improve participants' cognitive functions, health measures, and psychosocial health? 2. Is an individualised or group-based health education session better at improving cognitive, physical and psychosocial health in participants who did not respond to the DiSaB intervention? 3. How useful and practical is the DiSaB intervention, according to
1. participants and 2. nurses carrying out the intervention?
The investigators will compare a DiSaB intervention to a control condition (where participants do not undergo any intervention) to see if the DiSaB intervention works in improving participants' health.
The investigators will also compare individualised versus group health education sessions to see which session is better at improving the health of participants who did not respond to the DiSaB intervention.
Participants will
1. Complete cognitive assessments, questionnaires, and health tests before intervention, immediately after the intervention, and 6 months after the intervention 2. Either undergo no intervention, or undergo the DiSaB intervention over 2 months 3. Be randomly selected to attend focus group interviews
Local champions will complete questionnaires and attend focus group interviews after administering and/or co-facilitating the intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged 40 - 55 years old
Have hypertension, hyperlipidaemia and/or type-2 diabetes
Ability to provide written informed consent
Posses sufficient English language skills in reading, writing and speaking
Disqualifiers
Physical, visual and/or hearing impairment
Language impairment (i.e. severe dysarthria or aphasia)
Not within age range listed
Major or active psychiatric conditions
Trial design
Sequential
Treatments tested in this trial
Brain Health Training Programme
Other intervention"Train Your Brain (TYB)" - group-based cognitive intervention programme for mild cognitive impairments. This programme equips participants with knowledge on cognition and brain health, provide cognitive coping strategies and boost their confidence and maintain independence in daily activities.
Treatment groups
Trial outcomes
Primary outcomes
Change in heart rate
Heart rate will be measured on-site
Change in lipid levels
Information will be obtained from patients; HealthHub/Health Buddy/OneNUHS or other health apps
Change in HbA1c levels
Information will be obtained from patients; HealthHub/Health Buddy/OneNUHS or other health apps
Change in blood pressure
Blood pressure will be measured on-site
Secondary outcomes
Economic evaluation on the feasibility of DiSaB implementation using cost-effectiveness questionnaire
For evaluation of economics and further impact
Sponsors and contacts
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