Our research hypothesis is as follows: A step - by - step screening strategy based on screening technologies can resolve the issue of insufficient efficiency in the traditional scale - based screening model. Meanwhile, performing pathological diagnoses on patients with suspected cognitive impairment identified through screening is conducive to the further implementation of etiology - based treatment and intervention, thus bringing benefits to patients at the earliest possible stage.
By exploring the characteristic changes in gait, facial expressions, and language of patients with suspected cognitive impairment and analyzing their diagnostic efficiency for cognitive impairment patients, new ideas can be provided for the early diagnosis of the disease.
Through longitudinal observation of the changes in disease - related information during the progression and transformation of the disease, a predictive model for the early diagnosis of cognitive impairment and the prediction of disease progression can be constructed.
Adults aged 50 and above;
Residents of this community for at least one year, with established medical records;
Deny a history of cognitive impairment diseases (mild cognitive impairment, dementia, Alzheimer's, etc.) and the use of anti-dementia drugs (cholinesterase inhibitors or memantine, etc.);
Agree to participate in the study;
Self-reported or confirmed through inquiry that there is a severe mental disorder, such as bipolar disorder or schizophrenia, etc.
Suffering from a disease that makes it impossible to complete the cognitive assessment.
Residents aged 50 and above who were included in the communities from December 2025 to April 2026
Ecologic or community
Cross-sectional
Not listed
The diagnostic efficiency of the cognitive impairment screening and diagnosis protocol
The diagnostic efficiency will be measured by the area under curve（AUC）of receiver operating characteristic（ROC）curve.
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