Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes.
Recent research has focused on the development of blood-based tests, sometimes referred to as liquid biopsy tests, which aim to look for changes in the blood that could be linked to cancer. These tests are still under investigation and are not part of routine clinical care.
The purpose of this study is to evaluate several blood-based ovarian cancer tests. This will be done by comparing test results from people who have ovarian cancer with results from people who do not have cancer.
The study will also collect information from standard blood tests and genetic analyses to better understand how these results relate to ovarian cancer.
This study is for research purposes only. The blood-based tests being evaluated are investigational and are not used to make medical decisions or diagnoses for women taking part in the study.
Women, trans men and non-binary people with female reproductive organs
Aged ≥35 years*
Pathologically diagnosed, by biopsy, with EOC prior to surgical intervention or treatment
Presenting with adnexal mass suspicious of OC on imaging and scheduled for surgical resection or biopsy (and subsequent confirmation of EOC)
Prior history and any treatment for malignancy
Prior removal of either ovary for any reason
Pregnant or lactating
Any condition or circumstance that, in the opinion of the investigator, could interfere with the participant's ability to participate or comply with study requirements
National and Kapodistrian University of Athens
Lead sponsor
European Commission
Collaborator