About this trial
This study aims to evaluate the impact of different discontinuation intervals of GLP-1 receptor agonists prior to colonoscopy on bowel preparation quality and the need for repeat colonoscopy, in order to establish appropriate discontinuation recommendations.
Eligibility criteria
Qualifiers
Individuals who are scheduled to undergo total colonoscopy for any reasons
Age between 18 to 70 years.
ECOG Performance status is 0 or 1.
Written consent to participate in the study has been obtained.
Disqualifiers
• Presence of severe comorbid conditions that preclude the safe performance of colonoscopy (e.g., unstable angina, recent myocardial infarction, decompensated heart failure, chronic respiratory disease, or bleeding diathesis).
History of prior gastric, small bowel, or colorectal segmental resection (patients with isolated appendectomy are eligible).
Family history of hereditary colorectal cancer syndromes.
Current or prior diagnosis of inflammatory bowel disease.
Trial design
Treatments tested in this trial
- GLP-1 not stop for 1 week
- GLP-1 stop for 1 week
Treatment groups
Locations
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