Discontinuation Recommendations for GLP-1 Receptor Agonists Prior to Colonoscopy: A Randomized Controlled Trial in Taiwan.

ConditionGLP-1
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorFu Jen Catholic University Hospital

About this trial

This study aims to evaluate the impact of different discontinuation intervals of GLP-1 receptor agonists prior to colonoscopy on bowel preparation quality and the need for repeat colonoscopy, in order to establish appropriate discontinuation recommendations.

Eligibility criteria

Qualifiers

Individuals who are scheduled to undergo total colonoscopy for any reasons

Age between 18 to 70 years.

ECOG Performance status is 0 or 1.

Written consent to participate in the study has been obtained.

Disqualifiers

• Presence of severe comorbid conditions that preclude the safe performance of colonoscopy (e.g., unstable angina, recent myocardial infarction, decompensated heart failure, chronic respiratory disease, or bleeding diathesis).

History of prior gastric, small bowel, or colorectal segmental resection (patients with isolated appendectomy are eligible).

Family history of hereditary colorectal cancer syndromes.

Current or prior diagnosis of inflammatory bowel disease.

Trial design

Treatments tested in this trial

  • GLP-1 not stop for 1 week
  • GLP-1 stop for 1 week

Treatment groups

240 Participants
are divided into 2 treatment groups

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

FJUHRecruiting24352, New Taipei, TaiwanTaiwanTaiwan