Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain?

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorLinnaeus University

About this trial

The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain - related negative affect in individuals with chronic pain.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Above 18 years of age

Fluent in Swedish

Persistent chronic pain with duration > 6 months

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Emotional intervention

    Other intervention

    Emotional intervention Description: The participant will watch a short video-clip with negative emotional content while simultaneously experience experimentally induced pain.

  • Emotional intervention

    Other intervention

    Description: The participant will watch a short video-clip with positive emotional content while simultaneously experience experimentally induced pain.

  • Emotional intervention

    Other intervention

    Description: The participant will watch a short video-clip with neutral emotional content while simultaneously experience experimentally induced pain.

Treatment groups

180 Participants
are divided into 1 treatment group
Group A: Experimental: Negative emotion, positive emotion, neutral emotion, control with experimental painExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Pressure pain thresholds

Description: Pressure pain thresholds will be measured i kPa with a handheld algometer (Somedic AB).

Time frame
Day 1: baseline PPTs are measured, intervention 2.20 min follows and intervention PPTs are measured directly after the intervention. Recruitment for single appointments for each participant will take place for 4 months.

Secondary outcomes

1

Pain tolerance (time in seconds the left hand is immersed in cold water 1 degree C).

Description: The measure pain tolerance equals the time the time the participant keeps their left hand immersed in cold water (1 degree C), before they decide to withdraw their hand. This will be measured in seconds. For each participant, the maximum time to keep the hand immersed in water is 300 seconds. Participants are successively recruited for single appointments for 4 months.

Time frame
Day 1: During a single session (30 min), the participant will keep their hand immersed in cold water for as long as possible while watching a video. This time will be measured in seconds.
2

Pain intensity on the NRS

Participants will rate their perceived pain intensity on the NRS (Numerical Rating Scale) after the intervention (film-clip combined with pain induction using the cold pressor apparatus with cold water 1 degree C. This will take place on a single session appointment for each participant. Participants will be successively recruited for single session appointments for 4 months.

Time frame
Day 1: Pain intensity will be estimated at single session appointments (30 min) on the NRS (Numerical Rating Scale) after the intervention. Participants will be successively recruited for single session appointments for 4 months.
3

Pain-related negative affect on the NRS-A

Description: Perceived pain-related negative affect will be estimated on the NRS-A (Numerical Rating Scale- Anxiety) after the intervention (film-clip combined with pain induction with the cold pressor apparatus with cold water 1 degree C).The pain intensity will be estimated at every single session appointment (30 min) after the intervention on the NRS (Numerical Rating Scale). The participants will be successively recruited for single session appointments for 4 months.

Time frame
Day 1: Pain intensity will be estimated at single session appointments (30 min) on the NRS-A (Numerical Rating Scale-Anxiety) after the intervention. Participants will be successively recruited for single session appointments for 4 months.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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