Does Ethyl Chloride Spray Work?
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Chicago
About this trial
A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18 years and older
Receiving a corticosteroid injection in an upper or lower extremity (to include soft tissue and joint injections)
Disqualifiers
17 years old and younger
declines enrollment
Trial design
Design model
Parallel
Treatments tested in this trial
Ethyl Chloride
Other interventionTopical anesthetic that rapidly cools the skin and underlying tissues
Cold Saline Spray
Other interventionplacebo application of cold saline spray
Treatment groups
246 Participants
are divided into 3 treatment groupsGroup A: Freeze spray groupExperimental treatment 1 intervention
Group B: Placebo application of cold saline sprayPlacebo comparator 1 intervention
Group C: No spray prior to injectionNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
To determine if freeze spray usage before corticosteroid injections significantly reduces patient discomfort during the procedure as measured by pain scores before injection
Using the visual analog pain scale (0 no pain - 10 worst possible pain) to ask patients their pain rating and if freeze spray usage before corticosteroid injections significantly reduces patient discomfort during the procedure.
Time frame
10 minutes before subject receives injection2
To determine if freeze spray usage before corticosteroid injections significantly reduces patient discomfort during the procedure as measured by pain scores after injeciton
Using the visual analog pain scale (0 no pain - 10 worst possible pain) to ask patients their pain rating and if freeze spray usage before corticosteroid injections significantly reduces patient discomfort during the procedure.
Time frame
10 minutes after subject receives injection3
To assess patient perception of freeze spray efficacy in decreasing anxiety regarding injections.
Using the treatment satisfaction questionnaire for medication-II to ask patients their anxiety and if freeze spray usage before corticosteroid injections significantly reduces patient anxiety during the procedure.
Time frame
10 minutes after subject receives injection4
To assess their current overall status compared to their pre-injection baseline
Using the single assessment numeric evaluation (0% furthest from normal and 100% normal) to ask patients their current status
Time frame
10 minutes after subject receives injectionSponsors and contacts
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Source ClinicalTrials.gov