Dose Response of Exercise for Arthritis Management

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of South Carolina

About this trial

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18 years or older

Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia

Ability to read and write in English

Disqualifiers

Have any contraindications to exercise (besides arthritis)

Engage in >45 min/week of Actigraph assessed moderate to vigorous intensity activity

Are pregnant, breastfeeding, or planning to become pregnant in the next year

Are planning to relocate out of the Columbia, SC area in the next 12 months,

Trial design

Design model

Parallel

Treatments tested in this trial

  • DREAM Adaptive Intervention

    Behavioral

    6-month physical activity program (Dose Response of Exercise for Arthritis Management (DREAM)) which includes monthly phone coaching, Walk With Ease Guidebook, behavioral lessons, and a Fitbit. Participants may receive additional contact (email, text, or phone) if they struggle to meet activity goal.

Treatment groups

285 Participants
are divided into 3 treatment groups
Group A: 45 minutes/weekExperimental treatment 1 intervention
Group B: 90 minutes/weekExperimental treatment 1 intervention
Group C: 150 minutes/weekExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Physical function (6 Minute Walk Test)

Change in distance walked during the 6 minute walk test

Time frame
Baseline to 6 months

Secondary outcomes

1

Physical function (6 Minute Walk Test)

Change in distance walked during the 6 minute walk test

Time frame
Baseline to 12 months
2

Physical function (chair stands)

Change in chair stand repetitions

Time frame
Baseline to 6 months
3

Physical function (chair stands)

Change in chair stand repetitions

Time frame
Baseline to 12 months
4

Health Related Quality of Life - Physical

Change in the physical component score of the SF-12v2 Health Survey. Scores range from 0-100, with higher scores reflective of better health.

Time frame
Baseline to 6 months

Other outcomes

1

Physical activity (min/week)

Change in Actigraph-assessed moderate-to-vigorous intensity physical activity

Time frame
Baseline to 6 months
2

Physical activity (min/week)

Change in Actigraph-assessed moderate-to-vigorous intensity physical activity

Time frame
Baseline to 12 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of South Carolina

Lead sponsor

Centers for Disease Control and Prevention

Collaborator