Dresden Corneal Disease and Treatment Study
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorTechnische Universität Dresden
About this trial
The purpose of this study is long-term follow up of patients with corneal diseases to analyze the quality of surgical interventions and diagnosis. Corneal ectasia, especially keratoconus, is a corneal disease that leads to an irreversible loss of visual acuity while the cornea becomes steeper, thinner and irregular. For these patients, surgical intervention (e.g. corneal cross-linking) is performed, in case of disease progression. Overall, a long-term follow up is needed to evaluate an early disease progression as well as corneal stability after surgical intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
corneal disease
corneal ectasia
Disqualifiers
pregnancy
age under 18 years
Trial population
Patients with corneal diseases attending a University Hospital Corneal Diseases Service.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
corneal cross-linking
Procedure/SurgeryUV-A Irradiation and riboflavin
corneal topography and tomography
Diagnostic testDetailed Information about corneal tomography is used for diagnosis
Treatment groups
700 Participants
are divided into 1 treatment groupGroup A: Ectasia2 interventions
Trial outcomes
Primary outcomes
1
Follow-up intervals
To find the best follow-up intervals for keratoconus patients with or without progression of the disease
Time frame
15 years2
postoperative follow-up intervals
To find the best follow-up intervals for keratoconus patients after surgical Intervention.
Time frame
15 yearsSecondary outcomes
1
Assessment of treatment quality
What is the best treatment option for the individual patient?
Time frame
15 yearsSponsors and contacts
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Source ClinicalTrials.gov