About this trial
The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital
Need contraception
Able to use non-hormonal contraception during the study
Giving consent
Disqualifiers
Pregnancy or history of giving birth within 3 months
Breastfeeding within the 6 months
History of using DMPA within 12 months
History of using other types of hormonal birth control pills within 4 weeks
Trial design
Single group
Treatments tested in this trial
Drospirenone
Drug4 mg tablet once daily
Treatment groups
Trial outcomes
Primary outcomes
Cervical mucus by modified Insler score
Modified Insler score (ferning, spinnbarkeit, viscosity, cellularity) according to the World Health Organization (WHO) guidelines 2010 used for prediction and detection of ovulation. Score ≥9 favoring fertility, 5-8 intermediate, and ≤4 unfavorable to fertility Comparing pre-bariatric surgery with post-bariatric surgery
Secondary outcomes
Estrogen and progesterone levels versus time
Serum estrogen and progesterone levels will be measured to evaluate change over time (pattern and value) and assess ovulation
Number of Participants With Treatment-Related Adverse Events
Sponsors and contacts
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