Drug-induced Kidney Injury Model
ConditionAcute Kidney Injury
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorZhejiang Provincial People's Hospital
About this trial
To establish the prediction model of renal dysfunction in patients with drug-induced renal injury and study the prognosis of different drug treatments
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Drug-induce acute kidney injury
Disqualifiers
1.Dialysis patients; 2.No baseline creatinine; 3.Obstructive AKI; 4.Clinical data were incomplete.
Trial population
Drug-induced acute kidney injury
Trial design
Design model
Cohort
Time perspective
Other
Treatments tested in this trial
Observational study, no intervention
Other interventionObservational study, no intervention
Treatment groups
1,500 Participants
are divided into 1 treatment groupGroup A: Drug induced acute kidney injury1 intervention
Trial outcomes
Primary outcomes
1
Model performance metrics assessed by AUC-ROC, accuracy and F1-score using 10-fold cross-validation
The prognosis of renal function was evaluated by measuring creatinine and proteinuria by laboratory tests. Predict outcomes using machine learning methods. And the prediction effect of the prediction model was evaluated by AUC-ROC, F1, accuracy and other indicators.
Time frame
through study completion, an average of 6 monthsSecondary outcomes
1
The rate at which creatinine falls
Time frame
7 days, 1 month, 3 months after treatmentSponsors and contacts
Click on the lead sponsor to view all of their trials.
Zhejiang Provincial People's Hospital
Lead sponsor
Taizhou Enze Medical Center Group
Collaborator
Hangzhou Linping District first People's Hospital
Collaborator
Aksu district first People's Hospital
Collaborator
Ningbo Yinzhou District Second Hospital
Collaborator
Wucheng District First People's Hospital
Collaborator
Source ClinicalTrials.gov