Dynamic Cardio-vascular, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIRCCS Policlinico S. Donato

About this trial

IDEALE aims to assess the status of autonomic function, cerebral autoregulation (CA) and cortical activity in healthy subjects and correlate these functions with the psychological dimension of the subjects.

To this end, parameters of cardiac, cortical, vascular and cerebrovascular variability derived from electrocardiographic, electroencephalographic, respiratory movement, blood pressure, transcranial Doppler signals will be acquired and analysed for each healthy volunteer (TCD) and Laser-Doppler transcutaneous, during a phase of clinostatism (REST) and one of active orthostatism (STAND). In addition, volunteers will be submitted to psychometric tests (Chieti Affective Action Videos, CAAV) to assess the presence of depressive symptoms.

Eligibility criteria

Qualifiers

age older than 18 years

spontaneous sinus rhythm

signed informed consent

Disqualifiers

Definite diseases of the Autonomic Nervous System (SNA) or the cardiovascular system

Central nervous system disorders

subjects under drug therapy that may affect the cardiovascular system

pregnancy

Trial design

Treatments tested in this trial

  • Active standing

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators