Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke

ConditionHeat Stroke
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.

The main questions it aims to answer are:

* the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke. * the best body temperature at the cutting point of stop cooling. * The relationship between the volume and speed of ice saline infusion and the cooling effect.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.

Disqualifiers

need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.

Trial population

Comprehensive tertiary hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • observation

    Other intervention

    This study is an observational study. Patients will receive conventional cooling measures and organ function support.

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: Patients with heat stroke1 intervention

Trial outcomes

Primary outcomes

1

mortality

Number of participants who dead during hospitalization

Time frame
up to 90 days
2

organ damage

Number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver and coagulation

Time frame
up to 90 days

Secondary outcomes

1

continuous renal replacement therapy

Number of participants who need CRRT

Time frame
up to 90 days
2

length of ICU stay

The length patient stay in ICU

Time frame
up to 90 days
3

length of hospital stay

The length patient stay in hospital

Time frame
up to 90 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead sponsor

Yiwu Central Hospital

Collaborator

Jinhua People's Hospital

Collaborator

Jinhua Municipal Central Hospital

Collaborator

Dongyang People's Hospital

Collaborator

Lanxi People's Hospital

Collaborator