About this trial
The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.
The main questions it aims to answer are:
* the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke. * the best body temperature at the cutting point of stop cooling. * The relationship between the volume and speed of ice saline infusion and the cooling effect.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.
Disqualifiers
need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.
Trial population
Comprehensive tertiary hospital
Trial design
Cohort
Prospective
Treatments tested in this trial
observation
Other interventionThis study is an observational study. Patients will receive conventional cooling measures and organ function support.
Treatment groups
Trial outcomes
Primary outcomes
mortality
Number of participants who dead during hospitalization
organ damage
Number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver and coagulation
Secondary outcomes
continuous renal replacement therapy
Number of participants who need CRRT
length of ICU stay
The length patient stay in ICU
length of hospital stay
The length patient stay in hospital
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead sponsor
Yiwu Central Hospital
Collaborator
Jinhua People's Hospital
Collaborator
Jinhua Municipal Central Hospital
Collaborator
Dongyang People's Hospital
Collaborator
Lanxi People's Hospital
Collaborator