The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.
Age over 18 years
Signed consent to participate in the project and GDPR
Patients with new-onset and ongoing or progressive dyspnea (min. NYHA II) after a pulmonary embolism episode or worsening of dyspnea after a pulmonary embolism episode compared to the status before the episode (at least 1 HYHA grade) or
ECHO evidence of severe PH at diagnosis of PE (PASP >60 mmHg)
Not agreeing to participate in the project
Contraindications to treatment
Pacients matching all inclusion \& exclusion criteria
Cohort
Prospective
Standardized CTEPH Screening Protocol
Other interventionImplementation of a standardized screening algorithm for early detection of CTEPH in patients after Acute Pulmonary Embolism (APE) and establishment of optimized referral of patients to specialized centers.
Positive predictive value of initial examination
Examinations include echocardiography, CT scan or scintigraphy, and possibly other examinations determined by the cardiologist. Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the primary detection site.
CTEPH detection rates
Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the specialized centre.
Proportion of people with suspected CTEPH who attended a follow-up examination at a specialized pulmonary hypertension treatment centre
Examinations include echocardiography, CT scan or scintigraphy, and possibly other examinations determined by the cardiologist. Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the primary detection site.
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Institute of Health Information and Statistics of the Czech Republic
Lead sponsor
General University Hospital, Prague
Collaborator
