Early Detection of Vaping-related Vascular Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-40
SponsorUniversity of Miami
About this trial
The purpose of this study is to determine how vaping affects blood vessels, in particular if early damage occurs in the lung vessels.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Current electronic cigarette (EC) Puff Bar users defined as using EC either daily or occasionally in the past 30 days for at least 6 months, and with 5% nicotine concentration pods.
Adults aged 18-40 years
Healthy never smokers, never vapers
Adults aged 18-40 years
Disqualifiers
Current or past smoking of tobacco cigarette (TC) or other tobacco/nicotine products (e.g., smokeless tobacco, Hookah) or marijuana will be excluded from the study.
Subjects with self-reported history of chronic health problems including asthma, chronic obstructive pulmonary disease (COPD), morbid obesity (BMI>40 kg/m2), hypertension or diabetes
Pregnant or breastfeeding women
Trial population
Healthy non smokers and vapers residing in Florida
Trial design
Design model
Other
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
90 Participants
are grouped into 3 trial groupsGroup A: Healthy Volunteer Group
Group B: High Frequency Vaping Group
Group C: Low-Frequency Vaping Group
Trial outcomes
Primary outcomes
1
Airway blood flow reactivity (QAW)
QAW will be measured via soluble gas uptake method
Time frame
Up to 1 week2
Pulmonary vascular resistance (PVR)
PVR will be measured via echocardiography
Time frame
Up to 4 weeks3
Flow-mediated vasodilation (FMD)
FMD will be measured by blood pressure cuff deflation using ultrasound
Time frame
Up to 4 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Miami
Lead sponsor
Florida Department of Health
Collaborator
Source ClinicalTrials.gov