Early Intervention Strategies for Lung Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-74
SponsorThe First Affiliated Hospital of Guangzhou Medical University

About this trial

Low-dose CT (LDCT)can detect and treat lung cancer earlier and more quickly, while expanded screening coverage helps reduce the incidence and mortality of respiratory diseases such as lung cancer. This study aims to conduct a single-arm cluster randomized trial of digitally enabled LDCT in Guangzhou to assess its intervention effectiveness and cost-effectiveness.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

The community health service center must be located within one of the 11 districts of Guangzhou.

Disqualifiers

Inclusion Criteria Aged 40-75 years. Residing in the community participating in the study for a long time. No known history of lung cancer and has not undergone lung cancer screening in the past three months.

Exclusion Criteria Individuals diagnosed with lung cancer. Individuals with severe other health issues that make them unsuitable for CT imaging.

Trial design

Design model

Single group

Treatments tested in this trial

  • Low-dose CT screening

    Device

    Low-dose CT screening is conducted at primary healthcare institutions, and patients with detected lung nodules are referred to hospitals for further examination

  • AI full-lung model interpretation system

    Device

    Using artificial intelligence technology to assist in the interpretation of CT images

  • Digital Health Platform

    Device

    Community health centers and streets in Guangzhou use a program called "Fei Anxin" to manage residents' information in a unified way

Treatment groups

16,000 Participants
are divided into 1 treatment group
Group A: Digitally enabled low-dose CT screening GroupExperimental treatment 3 interventions

Trial outcomes

Primary outcomes

1

The early diagnosis rate of lung cancer

Time frame
Within 1 year after the intervention is implemented

Secondary outcomes

1

The number of participants in lung cancer screening

Time frame
Within 1 year after the intervention is implemented
2

Number of individuals with positive screening results

Time frame
Within one year after the intervention is implemented
3

3-month follow-up rate.

Time frame
Within three months after the intervention is implemented
4

One-year follow-up rate

Time frame
Within 1 year after the intervention is implemented

Other outcomes

Sponsors and contacts

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