A Study on the Live-Attenuated Herpes Zoster Vaccine for Sequential Booster Immunization Following Recombinant Herpes Zoster Vaccine

ConditionHerpse Zoster
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age50+
SponsorChangchun BCHT Biotechnology Co.

About this trial

Evaluate the immunogenicity after boost vaccination with the live attenuated herpes zoster vaccine.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age ≥ 50 years old;

The participant can provide personal informed consent and sign the informed consent form;

temperature ≤ 37.0℃ on the day of administration;

capable of complying with the requirements of the clinical trial protocol to complete the trial.

Disqualifiers

Subjects with immunodeficiency or immunosuppression caused by underlying diseases or treatments, including primary/acquired immunodeficiency (e.g., AIDS and other virus-induced immunodeficiency), hematologic malignancies (leukemia, lymphoma or other bone marrow/lymphoid neoplasms), ongoing immunosuppressive therapy, or radiotherapy/chemotherapy for malignancies.

Subjects with a history of allergic reaction to any component of the investigational product.

Subjects with acute infection or acute exacerbation of chronic infection (vaccination should be deferred).

Women of non-postmenopausal status with positive pregnancy test, pregnant or lactating women, or those planning pregnancy within 6 months.

Trial design

Design model

Single group

Treatments tested in this trial

  • live-attenuated zoster vaccine

    Biological/Vaccine

    one dose of live-attenuated zoster vaccine to the particpent only administered one dose of recombinant zoster vaccine

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: live-attenuated zoster vaccineExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

immunogenicity

IgG to gE/FAMA antibody/Cellular immune level

Time frame
30 days after administration

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: