Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women

Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexFemale
Age18-70
SponsorUniversity of Missouri-Columbia

About this trial

To determine if vascular beta3 adrenergic receptors are present and functional in aging women and can be targeted to attenuate sympathetic vasoconstriction and enhance vascular function in aging women.

Eligibility criteria

Qualifiers

Healthy women,

Assigned female at birth,

18-70 years of age,

Body mass index <18 or ≥30 kg/m2,

Disqualifiers

Assigned male at birth,

Pregnancy,

Breastfeeding,

History of hormone replacement therapy, chemical menopause, or oophor-ectomy

Trial design

Treatments tested in this trial

  • Placebo
  • Gemtesa

Treatment groups

60 Participants
are divided into 2 treatment groups