Bimatoprost as a Treatment for Graves' Orbitopathy

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorJohns Hopkins University

About this trial

Testing whether Bimatoprost, a topical eye drop used for glaucoma, can be used to induce periorbital fat atrophy in patients with Graves' disease

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Bimatoprost Ophthalmic

    Drug

    Bimatoprost, aka Lumigan, one drop in one eye nightly

Treatment groups

3 Participants
are divided into 2 treatment groups
Group A: Bimatoprost in more proptotic eyeExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Reduction in periorbital fat causing improvement in proptosis

Time frame
1 year

Secondary outcomes

Other outcomes

Sponsors and contacts

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