Collagenase Injection for Contracture Management
ConditionContracture
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-75
SponsorThe University of Texas Health Science Center, Houston
About this trial
The overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for contracture management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
Eligibility criteria
Qualifiers
≥ 6 months post stroke, brain injury or spinal cord injury, medically stable;
clinical diagnosis of tendon contracture
Disqualifiers
Is hypersensitive to XIAFLEX or collagenase;
Is currently adjusting tone alternating medications (e.g., baclofen), or
Received botulinum toxin injection to target areas <4 months, or phenol injections < 9 months;
Received surgical release of tendons;
Trial design
Treatments tested in this trial
- Active XIAFLEX Collagenase injection
Treatment groups
15 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov