Comparing Standard Platelet-Rich Plasma and Light-Enhanced Platelet-Rich Plasma for Treating Hair Loss in Androgenetic Alopecia: A Randomized Controlled Trial

ConditionAndrogenetic Alopecia

Trial statusNot yet recruiting

Trial phaseEarly Phase 1

Trial typeInterventional

Biological sexAll

Age18-65

SponsorKimberly Meathrel

About this trial

The goal of this clinical trial is to compare 3 different types of PRP in androgenetic alopecia patients. The main questions it aims to answer:

Does Redlight enhanced, Blue light enhanced, or traditional PRP result in higher hair density and health? Does Redlight enhanced, Blue light enhanced, or traditional PRP result in other improved hair metrics.

Participants will consent to a PRP treatment but will be blinded to the type. They will then be asked to return for Tricholab analysis at set post-operative timepoints to record changes in hair metrics (Baseline, 1 month, 3 months, 6 months, 9 months, 12 months).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-65

Diagnosed Androgenetic Alopecia

Willing to comply with protocol and follow up

Disqualifiers

Active scalp infection or disease

Prior PRP within last 6 months

Use of hair growth medication topical or oral

Platelet dysfunction or anticoagulation

Trial design

Design model

Parallel

Treatments tested in this trial

Platelet-Rich Plasma (PRP) Injections
Drug
Autologous platelet-rich plasma prepared from the participant's own peripherally drawn. Blood is processed via centrifugation to concentrate platelets and associated growth factors, then injected into the scalp across the area of hair thinning. Administered at each treatment visit per the study treatment schedule.
Red-light photobiomodulation with cooling
Device
Standard Intervention 1 with PRP undergoing additional Stimulus 1: 620 nm, 1 J/cm², 10 minutes; Stimulus 2: 4°C cooling, 15 minutes via MetaCell Technologies System.
Blue-light photobiomodulation
Device
Standard Intervention 1 with PRP undergoing additional Stimulus 1: 467 nm, 1 J/cm², 10 minutes; Stimulus 2: 37°C, 10 minutes using MetaCell Technologies System.

Treatment groups

30 Participants

are divided into 3 treatment groups

Group A: Standard PRPExperimental treatment 1 intervention

Group B: Red-Light Enhanced PRPExperimental treatment 2 interventions

Group C: Blue-Light Enhanced PRPExperimental treatment 2 interventions