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Efficacy of Dexmedetomidine vs Midazolam for Early Extubation in Critically Ill Agitated Patients Undergoing Weaning

ConditionAgitation, Emergence
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-60
SponsorSheikh Zayed Medical College

About this trial

Comparison of effect of dexmedetomidine and midazolam in icu patients who put on mechanical ventilation and show agitation on weaning.Selection of better agent minimises the drug related side effects like respiratory depression but also helps in weaning for early extubation,give hemodynamic stability and reduce morbidity and mortality in icu..

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

all patients with age <60 irrespective of gendre

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Dexmedetomidine Hydrochloride

    Drug

    Inj dexmedetomidine and inj midazolam given to two groups of participants and effects of both drugs will be observed for 24 hrs

Treatment groups

66 Participants
are divided into 2 treatment groups
Group A: DexmedetomidineExperimental treatment 1 intervention
Group B: MidazolamExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Effective sedation in icu patients lead to successful 1weaning in icu patients

Assess patients by using ramsay sedation score (score 1 =awake upto score 6=no response)

Time frame
Upto 48 hrs

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sheikh Zayed Medical College

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: